Background: The efficiency of in vitro maturation (IVM) has remained low despite extensive effort to understand the culture conditions. This study investigated the effect of cumulus cells and meiotic inhibitors on oocyte developmental competence in the presence of Alpha Lipoic acid (ALA) Materials and Methods: Mouse germinal vesicle oocytes were considered in cumulus-denuded oocytes (CDOs) and ...

This study examined the unique longitudinal effects linking academic competence, social competence, and internalizing symptoms from childhood to adulthood. A multimethod and multi-informant approach was used to assess psychopathology and competence in 205 participants during four developmental periods. Social competence in childhood had a cascading effect on internalizing symptoms in adolescenc...

Although adolescence is by many scholars viewed as a problematic developmental period, recent research efforts focus increasingly on the antecedents and consequences of what makes adolescents thrive (Smetana, Campione-Barr, & Metzger, 2006). Clearly, adolescence is a time of exploration and opportunity for many youth and adolescent researchers have recognized the importance of studying the mech...

purpose: to examine and compare the prevalence of different types of mental disorders among the administrative staff and warders of the central prison of sistan and baluchestan. materials and methods: the study population included all employees of zahedan general office of prisons. the sample consisted of 100 employees, of whom fifty individuals worked in various administrative units of zahedan...

Embryonic development relies on the capacity of progenitor cells to appropriately respond to inductive cues, a cellular property known as developmental competence. Here, we report that epigenetic priming of enhancers signifies developmental competence during endodermal lineage diversification. Chromatin mapping during pancreatic and hepatic differentiation of human embryonic stem cells revealed...

et al., 1996, 1998). It is thus apparent that in-vitro matured 1Centre for Early Human Development, Institute of Reproduction human oocytes display meiotic but not developmental and Development, Level 5, Monash University, Monash Medical competence. Centre, 246 Clayton Road, Clayton, Victoria, Australia 3168 and 2Department of Obstetrics and Gynaecology, National University of Meiotic and devel...